THE ROLE OF MICROBIOTA IN HUMAN IMMUNE SYSTEM MODULATION
DOI:
https://doi.org/10.71465/hjmri.258Keywords:
Microbiota, Immune Modulation, Gut-Immune Axis, DysbiosisAbstract
The human microbiota—comprising trillions of microbes residing primarily in the gut—plays a central role in the development, regulation, and function of the immune system. This dynamic interaction influences host immunity, inflammation, and resistance to infections. Disruption of microbial communities, or dysbiosis, has been linked to autoimmune disorders, allergies, and even neuroimmune conditions. This review highlights the key microbial species, immune mechanisms influenced by commensals, the impact of antibiotics and probiotics, and the emerging therapeutic interventions targeting the microbiota. We also discuss the microbiota research landscape in Pakistan and its implications for immune-related health outcomes.
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